Éva Csősz

LAST UPDATED: March 24, 2016.

Current appointment:

Assistant professor

Proteomics Core Facility Manager

Lipidomics Core Facility Manager

Department of Biochemistry and Molecular Biology, Faculty of Medicine, University of Debrecen, Debrecen, Hungary

Contacts:

 Office address:

 Department of Biochemistry and Molecular Biology, Research Center for  Molecular Medicine,  Faculty of Medicine, University of Debrecen

 Nagyerdei krt. 98., Debrecen, 4032

 Location: Theoretical Building, 208.

 Phone: +36-52-416432, +36-52-512900 ext 55734

 Fax: +36-52-314989

 Email: cseva(at)med.unideb.hu

General information:

 Languages:

 Hungarian (native)

 English (fluent, State Exam, CAE)

 Romanian (fluent)

Academic background:

 Doctor of Phylosophy in Biomedical Sciences (summa cum laude)(157/2008.PhD), University of Debrecen, Debrecen (2008)

 Cellular and Molecular Immunbiology Doctoral School, University of Debrecen, Debrecen, (2008)

 Ph.D. thesis entiteled:  Characterization of transglutaminase 2 substrate specificity using phage display technology, logistic regression analysis and intrinsic disorder examination (In English - 2008)

 Supervisor: Prof. Dr. Laszlo Fesus

 M.Sc. Degree (T-263/2001): Biology (spec. biochemistry),  University of Debrecen, Debrecen, (2001)

 M.Sc. Degree (A0000268): Cell and Molecular Biology,  Babes-Bolyai University, Cluj Napoca, (2001)

 B.Sc. Degree (0092805): Biology,  Babes-Bolyai University, Cluj Napoca, (1999)

Scientific background:

 Junior research fellow -  Department of Biochemistry and Molecular Biology,  Medical and Health Science Center,  University of Debrecen  (2008-2012)

 Instructor -  Laboratory of Biochemistry, Department of Animal Physiology, Faculty of Biology and Geology, Babes-Bolyai University, Cluj Napoca, Romania,  (2000-2001)

 Undergraduate student:

 Laboratory of Apoptosis Research, Department of Biochemistry and Molecular Biology, Research Center for Molecular Medicine,  Medical and Health Science Center, University of Debrecen, Debrecen, Hungary (1997-2001)

 Laboratory of Biochemistry, Department of Animal Physiology,  Faculty of Biology and Geology, Babes-Bolyai University,  Cluj Napoca, Romania  (1995-1999)

 Laboratory of Genetics, Department of Ecology,  Faculty of Biology and Geology, Babes-Bolyai University,  Cluj Napoca, Romania  (2000-2001)

Current membership in professional societies:

 Hungarian Biochemical Society, Member since 2003

 Hungarian Proteomics Society, Member since 2007

 Hungarian Chemical Society, Member since 2015

 Human Proteome Organization (HUPO), Member since 2014

Publications:

G. Gulyas, E. Csosz, J. Prokisch, A. Javor, M. Mezes, M. Erdely3, K. Balogh, T. Janaky, Z. Szabo, A. Simon, L. Czegledi (2016) Effect of nano-sized, elemental selenium supplement on the proteome of chicken liver, Journal of Animal Physiology and Nutrition, DOI: 10.1111/jpn.12459, IF: 1.406

Gábor Hutóczki, László Bognár, Judit Tóth, Beáta Scholtz, Gábor Zahuczky, Zoltán Hanzély, Éva Csősz, Judit Reményi-Puskár, Gergő Kalló, Tibor Hortobágyi, Almos Klekner (2015) Effect of concomitant radiochemotherapy on invasion potential of glioblastoma, . Pathol Oncol Res. 2016 Jan;22(1):155-60. doi: 10.1007/s12253-015-9989-5. Epub 2015 Oct 9. IF: 1.855

Álmos Klekner, Gábor Hutóczki, József Virga, Judit Reményi-Puskár, Judit Tóth, Beáta Scholtz, Éva Csősz, Gergő Kalló, László Steiner, Tibor Hortobágyi, László Bognár (2015) Expression pattern of invasion-related molecules in the peritumoral brain, Clin Neurol Neurosurg. 2015 Dec;139:138-43. doi: 10.1016/j.clineuro.2015.09.017. Epub 2015 Sep 26. IF: 1.127

Gerardo Alvarado, Viktória Jeney, Attila Tóth, Éva Csősz, Gergő Kalló, Thanh An Huynh, Csaba Hajnal, Judit Kalász, Enikő T. Pásztor, István Édes, Magnus Gram, Bo Akerström, Ann Smith, John W. Eaton, György Balla, Zoltán Papp, József Balla (2015) Heme-induced contractile dysfunction in human cardiomyocytes caused by oxidant damage to thick filament proteins, Free Radical Biology and Medicine 2015 Dec;89:248-62. doi: 10.1016/j.freeradbiomed.2015.07.158. Epub 2015 Sep 25. IF: 5.736

Gergő Kalló, Arunima Chatterjee, Márta Tóth, Éva Rajnavölgyi, Adrienne Csutak, József Tőzsér, Éva Csősz (2015) Relative quantification of human β-defensins by an SRM-based proteomics approach, Rapid Communications in Mass Spectrometry,29:1623–1631. IF: 2.253

Eva Csosz, Gabriella Emri, Gergő Kalló, George Tsaprailis, József Tőzsér (2015) Highly abundant defense proteins in human sweat as revealed by targeted proteomics and label free quantification mass spectrometry. Journal of the European Academy of Dermatology and Venereology, 29(10):2024-2031. doi: 10.1111/jdv.13221. Epub 2015 Aug 25. IF: 2,826

Torok Z, Peto T, Csosz E, Tukacs E, Molnar A, Maros-Szabo Z, Berta A, Tozser J, Hajdu A, Nagy V, Domokos B, Csutak A. (2013) Tear fluid proteomics multimarkers for diabetic retinopathy screening. BMC Ophthalmol. 13:40. doi: 10.1186/1471-2415-13-40. IF: 1.44

 Palicz Z, Jenes A, Gáll T, Miszti-Blasius K, Kollár S, Kovács I, Emri M, Márián T, Leiter E, Pócsi I, Csősz E, Kalló G, Hegedűs C, Virág L, Csernoch L, Szentesi P. (2013) In vivo application of a small molecular weight antifungal protein of Penicillium chrysogenum (PAF). Toxicol Appl Pharmacol. 269:8-16. IF: 3.975

 Csosz E,Boross P, Csutak A, Berta A, Tóth F, Póliska S, Török Z, Tőzsér J. (2012) Quantitative analysis of proteins in the tear fluid of patients with diabetic retinopathy. J Proteomics. 75:2196-2204. IF:5.074

Simon-Vecsei Z, Király R, Bagossi P, Tóth B, Dahlbom I, Caja S, Csosz E, Lindfors K, Sblattero D, Nemes E, Mäki M, Fésüs L, Korponay-Szabó IR (2012) A single conformational transglutaminase 2 epitope contributed by three domains is critical for celiac antibody binding and effects. Proc Natl Acad Sci USA 109:431-436. IF: 9.771

 Kiraly R, Csosz E, Kurtan T, Antus S, Szigeti K, Simon-Vecsei Z, Korponay-Szabo IR, Keresztessy Z, Fesus L (2009) Functional significance of five noncanonical Ca2+-binding sites of human transglutaminase 2 characterized by site-directed mutagenesis. FEBS J 276: 7083-7096. IF: 3.042

 Csosz E,Meskó B, Fésüs L (2009) Transdab wiki: the interactive transglutaminase substrate database on web 2.0 surface. Amino Acids 36:615-617. IF: 3.877

 Csosz E,Bagossi P, Nagy Z, Dosztanyi Z, Simon I, Fesus L (2008) Substrate preference of transglutaminase 2 revealed by logistic regression analysis and intrinsic disorder examination. J Mol Biol. 383:390-402. IF: 4.146

 Keresztessy Z, Csosz E, Harsfalvi J, Csomos K, Gray J, Lightowlers RN, Lakey JH, Balajthy Z, Fésüs L (2006) Phage Display Selection of Efficient Glutamine-donor Substrate Peptides For Transglutaminase 2. Protein Sci. 15:2466-2480. IF: 3.462

 Nemes Z, Petrovski G, Csosz E, Fésüs L (2005) Structure-function relationship of transglutaminase-a contemporary view. In: Mehta K, Eckert R (szerk.) Transglutaminases. Prog. Exp. Tum Res. Basel, Karger, 38:19-36. IF: 4.214

 Csosz E,Keresztessy Zs, Fésüs L (2002) Transglutaminase substrates: from test tube experiments to living tissues. Minerva Biotecnol. 14:149-153. IF: 0.217