András Mádi
Current appointment:
Senior research associate of Biochemistry and Molecular Biology,
Apoptosis and Genomics Research Group of the Hungarian Academy of Sciences, Research Center for Molecular Medicine, University of Debrecen, Hungary
(2001-)
Contacts:
Office address: Department of Biochemistry and Molecular Biology, ResearchCenter for Molecular MedicineMedical and HealthScienceCenter, University of Debrecen, HungaryLifeScienceBuilding, Egyetem tér 1.,Debrecen, Hungary H-4010 Location: LifeScienceBuilding, 3.111
Phone: +36-52-416432, +36-52-512900 ext 55734 Fax: +36-52-314989
Email:
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General information:
Languages:
Hungarian (native)
English (fluent, State Exam,)
Academic background:
Ph.D. certificate
(TTK-60/1998): Molecular and Cell Biology (summa cum laude)
University of Debrecen, Debrecen (1998)
Tile of Ph.D. thesis
"Characterization of transglutaminase in wild type and cell death mutant strains of Caenorhabditis elegans"
(In Hungarian with Summary in English - 1998)
Diplomas (M.Sc.equivalent)
(245/1992): Biology (biotechnology)
KossuthLajosUniversity of Sciences, Debrecen, (1992)
Diploma work entitled:
Optimation of the antibiotic production of Xaenorhabdus nematophilus 703, experiment on the separation and isolation of the active substances
(In Hungarian - 1992)
(245/1991): Biology (ecology)
KossuthLajosUniversity of Sciences, Debrecen, (1991)
Diploma work entitled:
Investigation of changes in the synthesis of secondary metabolites taking place on the action of stress-effects in Quercus petraea
(In Hungarian - 1991)
Scientific background:
Marie Curie Postdoctoral Research Fellow
at the ProteomeCenter, University of Rostock, Germany
(2002-2003)
Advisor: Michael O. Glocker Ph.D.
Research associate
at the Apoptosis and Signaling Research Group of the HungarianAcademy of Sciences, University of Debrecen, Hungary
(1999-2001)
Advisor: László Fésüs, D.Sc.
Junior research associate
at the Biophysical Research Group of the HungarianAcademy of Sciences, University of Debrecen, Hungary
(1997-1998)
Advisor: László Fésüs, D.Sc.
Ph.D.student
at theLaboratory of Apoptosis, Department of Biochemistry, Faculty of Medicine, University of Debrecen, Debrecen, Hungary
(1993-1996)
Undergraduate student
at the Department of Microbiology and Biotechnology, KossuthLajosUniversity of Scineces, Debrecen, Hungary
(1991-1992)
and
Department of Ecology, KossuthLajosUniversity of Scineces, Debrecen, Hungary
(1989-1990)
Current memberships in professional societies:
Hungarian Biochemical Society , Member since 1997
Publications:
(2007)
Mádi, A. (2007) The nematode Caenorhabditis elegans. In: Cell Biology (Szabó, G. ed.), in print, Medicina, Budapest, Hungary. (In Hungarian).
(2005)
Mádi, A. (2005) Being on the track of thimerosal. Acta Microbiologica et Immunologica Hungarica 52, 95-103.
Bálint, B.L., Szántó, A., Mádi, A., Bauer, U.M., Gábor, P., Benkő, Sz., Puskás, L.G., Davies, P.J.A., Nagy, L. (2005) Arginine methylation provides epigenetic transcription memory for retinoid-induced differentiation in myeloid cells. Molecular and Cellular Biology 25, 5648-5663.
Mádi, A., Kárpáti, L., Kovács, A., Muszbek, L., Fésüs, L. (2005) High-throughput scintillation proximity assay for transglutaminase activity measurement. Analytical Biochemistry 343, 256-262.
(2004)
Mádi, A., Hoffrogge, R., Blaskó, B., Glocker, M.O., Fésüs, L. (2004) Amine donor protein substrates for transglutaminase activity in Caenorhabditis elegans. Biochemical and Biophysical Research Communications 315, 1064-1069.Bantscheff, M., Ringel, B.,
Mádi, A., Schnabel, R., Glocker, M.O., Thiesen, H.-J. (2004) Differential proteome analysis and mass spectrometric characterization of germ line development-related proteins of Caenorhabditis elegans.Proteomics 4, 2283-2295.
Blaskó, B., Mádi, A., Fésüs, L. (2004) Structural elements responsible for transglutaminase activity of protein disulfide isomerases and thioredoxins. Journal of Biological Regulators and Homeostatic Agents 18, 1-8.
(2003)
Blaskó, B., Mádi, A., Fésüs, L. (2003) Thioredoxin motif of Caenorhabditis elegans PDI-3 provides Cys and His catalytic residues for transglutaminase activity. Biochemical and Biophysical Research Communications 303, 1142-1147.
Mádi, A., Pusztahelyi, T., Punyiczki, M., Fésüs, L. (2003) The biology of the Post-Genomic Era: the proteomics. Acta Biologica Hungarica 54, 1-14.
Mádi, A., Mikkat, S., Ringel, B., Thiesen, H-J., Glocker, M.O. (2003) Profiling stage-dependent changes of protein expression in Caenorhabditis elegans by mass spectrometric proteome analysis leads to the identification of stage-specific marker proteins. Electrophoresis 24, 1809-1817.
Mádi, A., Mikkat, S., Ringel, B., Ulbrich, M., Thiesen, H.-J., Glocker, M.O. (2003) Mass spectrometric proteome analysis for profiling temperature-dependent changes of protein expression in wild-typeCaenorhabditis elegans. Proteomics 3, 1526-1534.
(2002)
Fésüs, L., Tóth, R., Mádi, A. (2002) The history of the Apoptosis research. In: Apoptosis (Kopper, L., and Fésüs, L. eds.), pp 15-35, Medicina, Budapest, Hungary. (In Hungarian).
(2001)
Mádi, A., Kele, Z., Janáky, T., Punyiczki, M., Fésüs, L. (2001) Identification of protein substrates for transglutaminase in Caenorhabditis elegans. Biochemical and Biophysical Research Communications 283, 964-968.
Nemes, Z., Mádi, A., Marekov, L.N., Piacentini, M., Steinert, P.M., Fésüs L. (2001) Analysis of protein transglutamylation in apoptosis. Methods in Cell Biology 66, 111-133.
(1998)
Mádi, A., Punyiczki, M., di Rao, M., Piacentini, M., Fésüs, L. (1998) Biochemical characterization and localization of transglutaminase in wild type and cell death mutants of the nematode Caenorhabditis elegans. European Journal of Biochemistry 253, 583-590.
(1997)
Mádi, A., Punyiczki, M., Fésüs, L. (1997) Lessons to learn from the cell death and heat shock genes of Caenorhabditis elegans. Acta Biologica Hungarica 48, 303-318.
(1996)
Fésüs, L., Mádi, A., Balajthy, Z., Nemes, Z., Szondy, Z. (1996) Transglutaminase induction by various cell death and apoptosis pathways. Experientia 52, 942-949.
Fésüs, L., Nemes, Z., Piredda, L., Mádi, A., di Rao, M., Piacentini, M. (1996) Measurement of the induction, activity and products of tissue transglutaminase in cells undergoing apoptosis. In: Techniques in Apoptosis (Cotter, T.G., and Martin, S.J. eds.), pp 21-51, Portland Press, London, England.