Curriculum vitae
NAME: Tamas Sperka
DATE AND PLACE OF BIRTH: Jul 28, 1970, Hungary
CITIZENSHIP: Hungarian
OFFICE:
Department of Biochemistry and Molecular Biology, University of Debrecen, Medical and Health Science Center, Faculty of Medicine, Debrecen, Hungary
EDUCATION, DEGREES:
- Bachelor degree in Biology and Chemistry, Esterhazy Karoly Teacher Training College, 1994
- Master degree in Chemistry, Kossuth Lajos University of Sciences, 2000
BACKGROUND:
- Ph.D. Student, University of Debrecen, 2000-2005
- Research assistant, 2005-
MEMBERSHIPS IN PROFESSIONAL SOCIETIES:
- Hungarian Society of Biochemistry
PUBLICATIONS:
- Feher, A., Boross, P., Sperka, T., Oroszlan, S. and Tozser J. (2004)
Expression of the murine leukemia virus protease in fusion with maltose binding protein
in Escherichia Coli.
Protein Exp. Purif. 35, 62-68.
- Bagossi, P., Sperka, T., Feher, A., Kadas, J., Zahuczky, G., Miklossy, G., Boross, P., Tozser, J. (2005)
Amino acid preferences for a critical substrate binding subsite of retroviral proteases in type 1 cleavage sites.
Journal of Virology, 79, 4213-4218.
- Sperka, T., Pitlik, J., Bagossi, P., Tozser, J. (2005)
Beta-lactam compounds as uncompetitive inhibitors of HIV-1 protease.
Bioorganic & Medicinal Chemistry Letters, 15, 3086-3090.
- Feher, A., Boross, P., Sperka, T., Miklossy, G., Kadas, J., Bagossi, P., Oroszlan, S., Weber, I.T., Tozser, J. (2006)
Characterization of the murine leukemia virus protease and its comparison with the HIV-1 protease.
J. Gen. Virol., 87, 1321-1330.
- Sperka, T., Boross, P., Eizert, H., Tozser, J., Bagossi, P. (2006)
Effect of mutations on the dimer stability and the pH optimum of the human foamy virus protease.
Protein Engineering Design and Selection, 19, 369-375.
- Sperka, T., Miklossy, G., Tie, Y., Bagossi, P., Zahuczky, G., Boross, P., Matuz, K., Harrison, R.W., Weber, I.T., Tozser, J. (2007)
Bovine leukemia virus protease: comparison with human T-cell leukemia virus and human immunodeficiency virus proteases.
J. Gen. Virol., 88, 2052-2063.